Maria Paraskevopoulou, Dermatologist - Venereologist
Last updated: 20 October 2026

Jalupro Classic

Jalupro Classic is an injectable bio-revitalising mesotherapy that combines hyaluronic acid with a complex of 4 amino acids (glycine, L-proline, L-lysine, L-leucine). It activates fibroblasts to produce new collagen, restores radiance and firmness to dull skin and softens fine lines and laxity — on the face, neck, décolletage and body, with minimal downtime.

Collagen is the “scaffold” that keeps skin firm. With age and sun exposure, its production slows down and its breakdown speeds up, resulting in dullness, fine lines and laxity. Jalupro Classic is built on a simple idea: give the skin exactly the ingredients collagen is made from, together with hyaluronic acid for hydration. It is the first and best-known product of the Jalupro range, and at UniqSkin we use it both for prevention and to revitalise skin that has started to lose its vitality.

What is Jalupro Classic?

Jalupro Classic is a Swiss-patented injectable solution, certified as a medical device (CE, class III). Each pack contains:

Two vials of 100 mg lyophilised amino acids (in powder form).
Two ampoules of hyaluronic acid, 30 mg / 3 ml.

The two components are mixed right before treatment, producing a clear solution that spreads evenly in the skin.

It belongs to the category of heterologous mesotherapy (as opposed to autologous treatments such as PRF, which use the patient’s own blood) and is often also described as a skin booster. It is not a filler: it does not add volume, but improves the quality of the skin itself.

How it works

Fibroblasts are the skin cells that produce collagen and elastin. Jalupro Classic acts on them in two ways:

Amino acids supply fibroblasts with the raw material to synthesise new collagen, activate their metabolic activity and help slow down the breakdown of existing collagen.
Hyaluronic acid holds water, keeping the skin hydrated, and creates a favourable environment — a “molecular scaffold” — for fibroblasts to work in.

The skin therefore gains immediately in hydration and radiance, while gradually, over the following weeks, it gains density and elasticity.

The ingredients

Glycine: the most abundant amino acid in collagen — roughly one in every three amino acids in its structure.
L-proline: a key structural component of collagen that gives it stability.
L-lysine: essential for the “cross-links” that bind collagen fibres together and give them strength.
L-leucine: supports protein synthesis and tissue repair.
Hyaluronic acid: for hydration, radiance and a healthy environment for skin cells.

What it treats

Jalupro Classic is suitable for:

Dull, tired skin that has lost its radiance.
Fine lines and expression lines.
Skin laxity on the face and body — both for prevention and improvement.
Preventing elastosis, i.e. damage to the skin’s elastic fibres from sun and age.
Improving the appearance of scars, including acne scars, and stretch marks.

Treatment areas

Besides the face, Jalupro Classic gives very good results on:

The neck and décolletage.
The back of the hands.
The inner arms and inner thighs.
The abdomen, knees and elbows.

If the goal is cellulite, we use Alidya, an injectable treatment designed specifically for it. See all our body mesotherapy treatments.

Who it is for

Jalupro Classic is suitable for men and women of all skin types. It is an ideal choice:

For prevention, when the first signs of tiredness and dehydration appear.
For skin that needs radiance, hydration and firmness, without changing facial features.
For body care, in areas with laxity or stretch marks.

For more mature or severely dehydrated skin, Jalupro Super Hydro — with a higher concentration of hyaluronic acid plus peptides — may be preferable.

The benefits

Radiance and hydration from the very first session.
Firmness & elasticity, thanks to new collagen stimulation.
Smoothing of fine lines.
A more even texture and improved appearance of scars.
A natural result, without “filling”.

How it differs from other Jalupro products

Compared with Jalupro Super Hydro: Super Hydro contains 7 amino acids, 3 peptides and a much higher concentration of hyaluronic acid, so it is aimed at more mature or dehydrated skin. Classic is ideal for prevention, radiance and for treating larger areas of the body.
Compared with Jalupro HMW: HMW contains high-molecular-weight hyaluronic acid and is aimed at acne scars, deeper wrinkles and pronounced marks on the neck and décolletage, while Classic is ideal for radiance and prevention.
Compared with Jalupro Young Eye: Young Eye is designed exclusively for the delicate area around the eyes, while Classic is used on the face, neck, décolletage and body.

The procedure

Assessment: We start with a medical assessment of your skin and a discussion of your goals.
Preparation: The skin is cleansed and an anaesthetic cream is applied for 20–30 minutes.
Injection: The solution is mixed at the time of treatment and injected with a very fine needle into the dermis, as small, superficial wheals across the treatment area.
Duration: About 30–60 minutes, depending on the size of the areas treated.
Protocol: Usually 3–4 sessions at 1–2 week intervals. The course is repeated twice a year.
Results: Hydration and radiance show from the first session, while firmness improves gradually. Results last about 3–6 months, which is why two courses a year are recommended.

Before and after the treatment

Before:

Avoid alcohol and intense sun exposure in the preceding days.
If you take anticoagulant or antiplatelet medication, let us know — do not stop it without your doctor’s advice.
Come without make-up.

After:

Avoid make-up and intense exercise for 12–24 hours.
Avoid saunas, heat and sun for 2–3 days.
Use a gentle moisturiser and sunscreen daily.
You can return to your daily activities straight away.

Combining with other treatments

Jalupro Classic combines beautifully with:

Autologous PRF: combining the growth factors of PRF with the amino acids of Jalupro enhances rejuvenation.
Microneedling with Dermapen, for extra collagen stimulation and better texture and scars.
LED phototherapy (Dermalux), for soothing and radiance.
Jalupro Young Eye, for complete care that includes the eye area.

Safety

Jalupro Classic is biocompatible, with a very good safety profile. Small wheals appear at the injection points immediately after treatment and settle within a few hours; mild redness or, more rarely, small bruises may also occur. A medical assessment always comes first; the treatment is not recommended in cases of active infection or inflammation in the area, pregnancy/breastfeeding or a known allergy to any of the ingredients.

Frequently Asked Questions

Is it a filler?

No. Jalupro Classic does not add volume. It stimulates the skin to produce its own collagen, improving radiance, hydration and firmness.
Does it hurt?

The treatment is well tolerated, as an anaesthetic cream is applied first and very fine needles are used.
How many sessions do I need?

Usually 3–4 sessions at 1–2 week intervals. The course is repeated twice a year to maintain results.
How long do the results last?

About 3–6 months. That is why the treatment is planned as two courses a year.
Should I choose Classic or Super Hydro?

Classic is ideal for prevention, radiance and body areas. Super Hydro is preferred for more mature or severely dehydrated skin. A medical assessment will show which suits your skin.
Can it be combined with PRF?

Yes. Combining it with autologous PRF is one of the most effective options, as the growth factors of PRF and the amino acids of Jalupro work synergistically.

Conclusion

Jalupro Classic is a proven, gentle and effective mesotherapy that gives the skin the building blocks of collagen, together with hyaluronic acid for hydration. The result is skin that is more radiant, firmer and more rested, in a natural way. At UniqSkin we design a personalised protocol, on its own or combined with other treatments, for the best possible results.