Maria Paraskevopoulou, Dermatologist - Venereologist
Last updated: 20 October 2026

Jalupro HMW

Jalupro HMW is the boosted bio-revitalising mesotherapy of the Jalupro range. It combines high-molecular-weight hyaluronic acid (High Molecular Weight — hence “HMW”) with an amino-acid complex, and is designed for areas with more pronounced signs: acne scars, deep wrinkles and laxity, especially on the neck and décolletage.

Not all skin needs the same treatment. When the goal is simply radiance and hydration, a gentle mesotherapy is usually enough. But when the skin has deeper marks — acne scars, wrinkles that won’t fade, a neck with lines and laxity — it needs something more intensive. Jalupro HMW was created precisely for these cases, and at UniqSkin we use it when we want a more intensive rebuilding of the skin.

What is Jalupro HMW?

Jalupro HMW is a class III medical device from the same family as Jalupro Classic. Its pack contains:

A pre-filled syringe with 20 mg of high-molecular-weight hyaluronic acid (1,200–1,400 kDa).
A vial with 80 mg of amino-acid solution: glycine, L-proline, L-lysine and L-leucine.

The hyaluronic acid is mixed with the amino acids at the time of treatment, creating a denser, “fuller” solution than classic Jalupro.

How it works

Jalupro HMW works in two ways at once:

Amino acids are the building blocks of collagen. They give fibroblasts the raw material to produce new collagen and elastin, and activate their metabolic activity.
High-molecular-weight hyaluronic acid stays in the tissues longer than low-molecular-weight hyaluronic acid. It provides intense hydration and support to the skin, helping to “fill” and smooth scars and deeper lines.

The result is a more substantial rebuilding: the skin becomes denser, smoother and more resilient.

What it treats

Jalupro HMW is particularly effective for:

Acne scars, mainly atrophic (“pitted”) scars.
Deep wrinkles and pronounced expression lines.
Neck wrinkles and laxity (neck “rings”).
Décolletage wrinkles, often the result of photo-ageing.
Thin, tired skin that has lost its density.

Treatment areas

Face, especially areas with scars or deeper wrinkles.
Neck and décolletage, where it gives some of its best results.
Back of the hands.
Body areas with laxity, such as the inner arms.

How it differs from other Jalupro products

Compared with Jalupro Classic: Classic contains lower-molecular-weight hyaluronic acid and is ideal for radiance and prevention. HMW, with high-molecular-weight hyaluronic acid, is “stronger” and aimed at scars and deeper marks. It also needs fewer sessions.
Compared with Jalupro Super Hydro: Super Hydro, with peptides and a very high concentration of hyaluronic acid, mainly targets intensive hydration of mature and dehydrated skin. HMW focuses more on scars and wrinkles.
Compared with Jalupro Young Eye: Young Eye is designed exclusively for the area around the eyes.

The benefits

Improved acne scars and skin texture.
Smoothing of deeper wrinkles.
Firming on the neck and décolletage.
New collagen, produced naturally.
Intense hydration and radiance.
Fewer sessions than classic mesotherapy.

The procedure

Assessment: We assess your skin, the type of scars or wrinkles and your goals.
Preparation: The skin is cleansed and disinfected, and an anaesthetic cream is applied for about 30 minutes.
Injection: The solution is mixed at the time of treatment and injected into the dermis with a fine needle. The technique is adapted to the area: linear injections along a wrinkle, multiple small injections over a scarred area, or a “fan” technique over larger surfaces.
Duration: About 30–45 minutes.
Protocol: Usually 2–3 sessions at 1–2 week intervals. The course is repeated twice a year.
Results: Hydration shows from the first session, while scars and wrinkles improve gradually as new collagen is produced. Results last about 3–6 months.

Before and after the treatment

Before:

Avoid alcohol and intense sun exposure in the preceding days.
If you take anticoagulant or antiplatelet medication, let us know — do not stop it without your doctor’s advice.
Come without make-up.

After:

Avoid make-up and intense exercise for 12–24 hours.
Avoid saunas, heat and sun for a few days.
Use SPF 50 sunscreen daily for at least 2 weeks.
You can return to your daily activities straight away.

Combining with other treatments

Jalupro HMW enhances the results of other collagen-stimulating treatments:

Fractional Laser CO2 and microneedling with Dermapen, for acne scars.
Autologous PRF, for extra growth factors.
Botox, for expression lines in the upper face.
LED phototherapy (Dermalux), for soothing and faster recovery.

Safety

Jalupro HMW is biocompatible, with a very good safety profile. After treatment, small wheals appear at the injection points and are absorbed within a few hours; mild redness or small bruises may also occur and resolve within a few days. A medical assessment always comes first; the treatment is not recommended in cases of active infection or inflammation in the area (such as active acne), pregnancy/breastfeeding or a known allergy to any of the ingredients.

Frequently Asked Questions

What does “HMW” mean?

It stands for High Molecular Weight. It refers to the product’s hyaluronic acid, which stays in the tissues longer and gives the skin more support.
Is it suitable for acne scars?

Yes, it is one of its main indications, especially for atrophic scars. For deeper scars it is often combined with Fractional Laser CO2 or Dermapen for better results.
Classic or HMW?

Classic is ideal for radiance, hydration and prevention. HMW is preferred when there are scars, deeper wrinkles or pronounced marks on the neck and décolletage.
Does it hurt?

The treatment is well tolerated, as an anaesthetic cream is applied for about 30 minutes beforehand.
How many sessions do I need?

Usually 2–3 sessions at 1–2 week intervals, twice a year.
Can I have it if I have active acne?

Not on areas with active inflammatory lesions. We first treat the acne and then the scars.

Conclusion

Jalupro HMW is the Jalupro option for skin with acne scars, deeper wrinkles or pronounced marks on the neck and décolletage. By combining high-molecular-weight hyaluronic acid with amino acids, it rebuilds the skin gradually and naturally. At UniqSkin we design a personalised protocol, on its own or combined with other treatments, for the best possible results.